15(S)-Fluprostenol isopropyl ester

公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）!

试剂描述：

产品名称：15(S)-Fluprostenol isopropyl ester

产品别名：15(S)-Flu-Ipr;

CAS号：1420791-14-5

英文别名：15(S)-Fluprostenol isopropyl ester

分子量：500.6

分子式：C₂₆H₃₅F₃O₆

纯度：≥98%

外观：见爱必信官网

保存方法：Store at -20℃

描述：15(S)-Fluprostenol isopropyl ester (15(S)-Flu-Ipr) is the unnatural C-15 epimer of Travoprost. Travoprost is the Alcon trade name for fluprostenol isopropyl ester, (Flu-Ipr) an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug.^1,2 Flu-Ipr is a prodrug which is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid. The free acid, fluprostenol, is a potent FP receptor agonist.³ In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity. Although data is currently not available for the activity of 15(S)-Flu-Ipr, inversion of the stereochemistry at the 15 position of ocular hypotensive prostaglandins generally lowers the potency approximately 100 fold.⁴

应用：见爱必信官网

产品信息订购：

产品更多信息请进入爱必信网站咨询