PtdIns-(1,2-dipalmitoyl) (ammonium salt)

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产品名称：PtdIns-(1,2-dipalmitoyl) (ammonium salt)

产品别名：DPPI;Phosphatidylinositol C-16;

CAS号：34290-57-8

英文别名：Ammonium (2R)-2,3-bis(palmitoyloxy)propyl (1S,2R,3R,4S,5S,6R)-2,3 ,4,5,6-pentahydroxycyclohexyl phosphate

分子量：828.1

分子式：C₄₁H₇₈O₁₃P • NH₄

纯度：≥98%

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保存方法：Store at -20℃

描述：The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.^1,2 PtdIns-(1,2-dipalmitoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) featuring C₁₆:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as that of the natural compound. PtdIns are phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P₂; PIP₂), and triphosphates (PtdIns-P₃; PIP₃). Hydrolysis of PtdIns-(4,5)-P₂ by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP₃) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.

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