O-2545 (hydrochloride)

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产品名称：O-2545 (hydrochloride)

产品别名：(6aR,10aR)-3-[6-(1H-Imidazol-1-yl)-2-methyl-2-hexanyl]-6,6,9-trim ethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol hydrochlorid e (1:1)

CAS号：874745-43-4

英文别名：(6aR,10aR)-3-[6-(1H-Imidazol-1-yl)-2-methyl-2-hexanyl]-6,6,9-trim ethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol hydrochlorid e (1:1)

分子量：445

分子式：C₂₆H₃₆N₂O₂ • HCl

纯度：≥98%

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保存方法：Store at -20℃

描述：Cannabinoid agonists are typically highly lipophilic compounds that require solubilization with either a surfactant agent or adherence to a water miscible substance such as albumin, Tween 80, or Emulphor. O-2545 is a potent water-soluble agonist of central cannabinoid (CB₁) and peripheral cannabinoid (CB₂) receptors with K_i values of 1.5 and 0.32 nM, respectively.¹ When dissolved in saline, O-2545 was highly efficacious in mouse behavioral models when administered either intravenously or intracerebroventricularly.¹

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