Calcipotriol (hydrate)

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产品名称：Calcipotriol (hydrate)

产品别名：Calcipotriene;

CAS号：112828-00-9

英文别名：Calcipotriene

分子量：412.6

分子式：C₂₇H₄₀O₃ · H₂O

纯度：≥98%

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保存方法：Store at -20℃

描述：Calcipotriol (hydrate) is a low-calcemic vitamin D receptor (VDR) agonist. Calcipotriol (hydrate) is about 200 times less potent in its effects on calcium metabolism than vitamin D (1,25[OH]D₃).¹ Binding of calcipotriol (hydrate) to the VDR increases AP-1, a transcription factor important for keratinocyte differentiation, and reduces expression of JunB protein, a transcriptional activator in the inflammatory response.² Calcipotriol (hydrate) also induces expression of thymic stromal lymphopoietin, which triggers T-cell differentiation in keratinocytes.³

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