4-Quinolone-3-Carboxamide Furan CB2 Agonist

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产品名称：4-Quinolone-3-Carboxamide Furan CB2 Agonist

产品别名：4Q3C CB₂ Agonist;

CAS号：1314230-75-5

英文别名：4-Quinolone-3-Carboxamide Furan CB2 Agonist

分子量：488.6

分子式：C₃₀H₃₆N₂O₄

纯度：≥98%

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保存方法：Store at -20℃

描述：Agonists of the peripheral cannabinoid (CB) receptor CB₂ may have antinociceptive and anti-inflammatory effects, as well as prevent osteoporosis.^1,2 4-Quinolone-3-carboxamide Furan CB₂ Agonist is a high-affinity ligand of CB₂ (K_i = 8.5 nM) with little affinity for CB₁ (K_i >10,000 nM).³ This compound demonstrates antinociceptive efficacy in the mouse formalin test at 1 mg/kg, an action which is blocked by a CB₂-selective antagonist, AM630 (Item No. 10006974).³

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