1-Palmitoyl Lysophosphatidic Acid

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产品名称：1-Palmitoyl Lysophosphatidic Acid

产品别名：1-Palmitoyl LPA (free acid);

CAS号：22002-85-3

英文别名：(2-hydroxy-3-phosphonooxypropyl) hexadecanoate

分子量：410.5

分子式：C₁₉H₃₉O₇P

纯度：≥98%

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保存方法：Store at -20℃

描述：1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of at least five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.^1,2 Additionally, 1-palmitoyl LPA enhances the action of β-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of P. aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca²⁺ and Mg2+.³

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