17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide

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产品名称：17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide

产品别名：17-phenyl trinor PGF_2α cyclopropyl methyl amide;

CAS号：1138395-10-4

英文别名：N-(cyclopropylmethyl)-7-[3,5-dihydroxy-2-(3-hydroxy-5-phenylpent-1-enyl)cyclopentyl]hept-5-enamide

分子量：441.6

分子式：C₂₇H₃₉NO₄

纯度：≥98%

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保存方法：Store at -20℃

描述：Prostaglandin F_2α (PGF_2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis. 17-phenyl trinor PGF_2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF_2α.¹ It is produced in vivo by the hydrolysis of 17-phenyl trinor PGF_2α ethyl amide.² 17-phenyl trinor PGF_2α ethyl amide is used to reduce intraocular pressure related to glaucoma.³ 17-phenyl trinor PGF_2α cyclopropyl methyl amide is a lipophilic analog of 17-phenyl trinor PGF_2α. Amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.

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