Keratinocyte Differentiation Inducer,3-[3-[2-(3,4,5-trimethoxyanilino)pyrrolo[2,3-d]pyrimidin-7-yl]phenyl]propanenitrile,863598-09-8

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产品名称：Keratinocyte Differentiation Inducer

产品别名：3-[3-[2-(3,4,5-trimethoxyanilino)pyrrolo[2,3-d]pyrimidin-7-yl]phenyl]propanenitrile

CAS号：863598-09-8

英文别名：3-[3-[2-(3,4,5-trimethoxyanilino)pyrrolo[2,3-d]pyrimidin-7-yl]phenyl]propanenitrile

分子量：429.5

分子式：C₂₄H₂₃N₅O₃

纯度：0.957

外观：见爱必信官网

保存方法：Store at 4° C

描述：Keratinocyte Differentiation Inducer cell-permeable pyrrolo-pyrimidone compound that acts as a potent, ATP-competitive inhibitor of casein kinase II (IC₅₀ = 9 nM) and an effective inducer of normal human keratinocytes (NHEK) differentiation (EC₅₀ = 100 nM). Also reported to interact, direcly or indirectly, with cellular TANK-binding Kinase 1 (TBK1) and NIMA-related kinase 9 (NEK9).

应用：A cell-permeable ATP-competitive inhibitor of caseing kinase II

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