Oleoyl Ethanolamide-d4,(9Z)-N-[2-Hydroxy(²H₄)ethyl]-9-octadecenamide,946524-36-3

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产品名称：Oleoyl Ethanolamide-d4

产品别名：OEA-d4; Oleic Acid Ethanolamide-d4

CAS号：946524-36-3

英文别名：OEA-d4; Oleic Acid Ethanolamide-d4

分子量：329.55

分子式：C₂₀H₃₅D₄NO₂

纯度：见爱必信官网

外观：Solution

保存方法：Desiccate at -20° C

描述：Oleoyl ethanolamide (OEA) is an analog of the endocannabinoid AEA found in brain tissue and in chocolate. It is one of the long chain fatty acid ethanolamides that accumulates rapidly in infarcted tissue but its biosynthesis is reduced in the intestine of rats following food deprivation. OEA is an endogenous, potent agonist for PPARα, exhibiting an EC50 value of 120 nM in a transactivation assay. Systemic administration of OEA suppresses food intake and reduces weight gain in rats (10 mg/kg intraperitoneally) and PPARα wild-type mice, but not in PPARα knockout mice. These data indicate that OEA regulates food intake by a PPARα-mediated mechanism.

应用：An internal standard for the quantification of oleoyl ethanolamide

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