N-cyclopentyl-N,N-dimethyl-3,4-bis(tetradecyloxy)-benzenemethanaminium, iodide,cyclopentyl-[[3,4-di(tetradecoxy)phenyl]methyl]-dimethylazanium,iodide,1202208-36-3

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产品名称：N-cyclopentyl-N,N-dimethyl-3,4-bis(tetradecyloxy)-benzenemethanaminium, iodide

产品别名：cyclopentyl-[[3,4-di(tetradecoxy)phenyl]methyl]-dimethylazanium,iodide

CAS号：1202208-36-3

英文别名：cyclopentyl-[[3,4-di(tetradecoxy)phenyl]methyl]-dimethylazanium,iodide

分子量：756

分子式：C₄₂H₇₈INO₂

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保存方法：Store at -20° C

描述：Lipid A is a lipid-rich component of endotoxin, also known as lipopolysaccharide (LPS), which in turn is part of the outer membrane of Gram-negative bacteria. Lipid A activates toll-like receptor 4 (TLR4), initiating an immune response. An antagonist of Lipid A activation of TLR4, exhibiting an IC50 value of 1.68 μM in a cell-based assay using modified human embryonic kidney (HEK) cells. It does not significantly affect HEK cell viability. In a model of sepsis, this chemical dramatically and significantly improves survival of mice given intraperitoneal LPS

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