1,2-benzoxazol-3-ylmethanesulfonamide,唑尼沙胺,68291-97-4

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试剂描述：

产品名称：1,2-benzoxazol-3-ylmethanesulfonamide

产品别名：Zonisamide

CAS号：68291-97-4

英文别名：Zonisamide

分子量：212.23

分子式：C₈H₈N₂O₃S

纯度：见爱必信官网

外观：Crystalline powder

保存方法：Store at room temperature

描述：1,2-benzoxazol-3-ylmethanesulfonamide (Zonisamide) is an antiepileptic with a wide range mechanistic and anticonvulsant profile. It has been shown to block voltage-sensitive T-type Ca²⁺ and Na⁺ channels, and stimulate BKCa channels. It has also been shown to modulate glutamate, monoamine, and GABA neurotransmission. It is reported to scavenge nitric oxide and hydroxyl free radicals, and inhibit lipid peroxidation. It exhibits antiParkinsonian and neuroprotective activity.

应用：An anticonvulsant blocker of voltage-sensitive T-type Ca²⁺ and Na⁺ channels

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