NSC 721648,2-(3,4-dimethoxyphenyl)-5-fluoro-1,3-benzothiazole,872726-44-8

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试剂描述：

产品名称：NSC 721648

产品别名：2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole; GW 610

CAS号：872726-44-8

英文别名：2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole; GW 610

分子量：289.32

分子式：C₁₅H₁₂FNO₂S

纯度：见爱必信官网

外观：Crystalline

保存方法：Store at -20° C

描述：NSC 721648 is a cell-permeable benzothiazole compound that exhibits potent in vitro antiproliferative activity against HCC 2998, IGROV1, MCF-7, MDA 468, SR, and T-47D (GI₅₀ <1 nM), while showing much reduced effect against 50 other human tumor cells in a panel screening. Although it is a high affinity AhR ligand (IC₅₀ = 25 nM; K_i = 6.8 nM in a TCDD competitive binding study) and a known CYP1A1 inducer, neither property can fully account for its antitumor activity.

应用：An antiproliferative benzothiazole compound

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