Gilvocarcin V,褐黄癌菌素V,77879-90-4

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产品名称：Gilvocarcin V

产品别名：褐黄癌菌素V

CAS号：77879-90-4

英文别名：DC-38-V

分子量：494.5

分子式：C₂₇H₂₆O₉

纯度：>95%

外观：Crystalline

保存方法：Store at -20° C

描述：Gilvocarcin V is the major analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces sp. Gilvocarcin V contains a vinyl group in the 8-position and is the most potent analogue of the complex. It is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. The metabolite displays potent antibacterial, antifungal, antiviral and antitumor activity. Recent research on the gilvocarcins suggests that they act as photoactivated crosslinkers of DNA to histones. Gilvocarcin V has also been shown to be cytotoxic against Gram-positive bacteria. Mediates a unique cross-linking reaction between DNA and histidine H3. And is shown to be weakly active against Gram-negative bacteria, fungi and tumors. Also an antineoplastic and a photosensitizing compound.

应用：A metabolite that displays potent antibacterial, antifungal and antiviral activity

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