R-Palmitoyl-(2-methyl) Ethanolamide,N-[(2R)-2-hydroxypropyl]hexadecanamide,179951-56-5

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产品名称：R-Palmitoyl-(2-methyl) Ethanolamide

产品别名：N-[(2R)-2-hydroxypropyl]hexadecanamide

CAS号：179951-56-5

英文别名：N-[(2R)-2-hydroxypropyl]hexadecanamide

分子量：313.5

分子式：C₁₉H₃₉NO₂

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保存方法：Store at 4° C

描述：A metabolically stable analog of the anti-inflammatory cannabinoid, palmitoyl ethanolamide (PEA) which is an endogenous cannabinoid found in brain, liver, and other mammalian tissues. PEA has also been isolated from egg yolk, and found to have anti-anaphylactic and anti-inflammatory activity in vitro. RP-2ME is a synthetic analog of PEA which incorporates an (R)-methyl group vicinal to the alcohol on the ethanolamine moiety. RP-2ME inhibits FAAH-mediated hydrolysis of AEA by 54% at a concentration of 100 µM. It also has weak CB receptor affinity, in that 100 µM inhibits agonist binding (1 nM CP55940 or WIN55212-2) only 26% and 15.5% at the human CB1 and CB2 receptors, respectively.

应用：A metabolically stable analog of palmitoyl ethanolamide

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