4'-Hydroxy Atomoxetine β-D-Glucuronide,4’-Hydroxy Atomoxetine -D-Glucuronide,540729-08-6

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产品名称：4'-Hydroxy Atomoxetine β-D-Glucuronide

产品别名：4’-Hydroxy Atomoxetine -D-Glucuronide

CAS号：540729-08-6

英文别名：4’-Hydroxy Atomoxetine -D-Glucuronide

分子量：447.48

分子式：C₂₃H₂₉NO₈

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保存方法：Store at -20° C

描述：4'-Hydroxy Atomoxetine ∫-D-Glucuronide is a metabolite of Tomoxetine. Tomoxetine (Atomoxetine, LY 139603; ) is a competitve and specific inhibitor of norepinephrine reuptake while demonstrating weak serotonin and dopamine inhibition as studied in synaptosomes of rat hypothalamus. Additional studies indicate that this (-) optical isomer is more effective than the (+) isomer, LY139602 (ent S-(+)-Atomoxetine Hydrochloride; ). Additionally, in the prefrontal cortex of rats, Tomoxetine was reported to not cause an increase in dopamine within the striatum or nucleus accumbens which may be useful in additional research studies investigating the reward pathways of the brain.

应用：A metabolite of Tomoxetine

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