IL-1R Antagonist,IL-1R Antagonist,566914-00-9

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产品名称：IL-1R Antagonist

产品别名：BB-loop Mimic; Hydrocinnamoyl-L-valyl Pyrrolidine

CAS号：566914-00-9

英文别名：BB-loop Mimic; Hydrocinnamoyl-L-valyl Pyrrolidine

分子量：302.41

分子式：C₁₈H₂₆N₂O₂

纯度：≥95%

外观：Oil

保存方法：Store at 4° C

描述：IL-1R Antagonist is a cell-permeable, end protected L-valyl derivative modeled on the MyD88-binding sequence of the TIR domain BB-loop of IL-1RI. It specifically inhibits TIR domain-mediated MyD88/IL1-RI interaction without affecting TLR4/MyD88 interaction. Has shown to activate the MAP kinase signaling cascades in murine lymphocytes and EL4 thymoma cells in vitro.

应用：A specific inhibitor of TIR domain-mediated MyD88/IL1-RI interaction

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