tetranor-PGEM-d6,8-[(1R,2R,5R)-2-(2-Carboxyethyl)-5-hydroxy-3-oxocyclopentyl]-6-oxo(2,2,3,3,4,4-²H₆)octanoic acid,1240398-16-6

公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）!

试剂描述：

产品名称：tetranor-PGEM-d6

产品别名：tetranor-Prostaglandin E Metabolite-d6

CAS号：1240398-16-6

英文别名：tetranor-Prostaglandin E Metabolite-d6

分子量：334.39

分子式：C₁₆H₁₈O₇D₆

纯度：见爱必信官网

外观：A solution in methyl acetate

保存方法：Store at -80° C

描述：

tetranor-PGEM-d6 contains six deuterium atoms at the 13, 13', 14, 14', 15, and 15' positions and is intended for use as an internal standard for the quantification of tetranor PGEM by GC- or LC-mass spectrometry. Tetranor PGEM-d6 is the major urinary metabolite of PGE1 and PGE2 and is used as a urinary marker of PGE2 biosynthesis, and to monitor metabolism after infusion or injection of PGE1 as a pharmaceutical. Normal healthy males excrete 16-30 µg of tetranor PGEM over a 24-hour period. Females excrete less by about a factor of three. Following oral administration (4 x 50 mg/24 hours) of the COX inhibitor, indomethacin, urinary levels of tetranor PGEM decrease by 75-98% indicating the almost complete loss of PGE2 biosynthesis.

应用：A compound used as an internal standard for quantification of tranor PGEM by GC-mass Specrometry

产品信息订购：

产品更多信息请进入爱必信网站咨询