Cytochalasin A,细胞松驰素 A,14110-64-6

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产品名称：Cytochalasin A

产品别名：Dehydrophomin

CAS号：14110-64-6

英文别名：Dehydrophomin

分子量：477.59

分子式：C₂₉H₃₅NO₅

纯度：≥98%

外观：Powder

保存方法：Store at -20° C

描述：Cytochalasin A is used in actin polymerization studies. Cytochalasin A is a metabolite of the fungus Drechslera dematoidea which binds to the barbed end of actin filaments resulting in inhibition of both the association and dissociation of subunits. Used as a tool for cytological research. The class of Cytochalasin fungal toxins are related by their chemical structure characterized by a highly substituted hydrogenated isoindole ring to which is fused a macrocyclic ring. Cytochalasin A is the oxidized analog of cytochalastin B . As opposed to other Cytochalasins, Cytochalasin A and cytochalasin B bind to the glucose transporter and inhibit monosaccharide transport across the plasma membrane. Cytochalasin A is sulfhydryl-reactive, and was shown to inhibit growth and sugar uptake in a Saccharomyces strain. Inhibits HIV-1 protease .
Other Cytochalasins available: Cytochalasin C ; Cytochalasin D ; Cytochalasin E, Aspergillus clavatus ; Cytochalasin H ; Cytochalasin J

应用：An HIV-1 protease inhibitor, antibiotic, glucose transport inhibitors, and actin polymerization inhibitor

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