Macbecin I,Macbecin I,(15R)-6,17-Didemethoxy-15-methoxy-6-methyl-11-O-methyl-geldanamycin,73341-72-7

公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）!

试剂描述：

产品名称：Macbecin I

产品别名：(15R)-6,17-Didemethoxy-15-methoxy-6​-methyl-11-O-methyl-geldanamycin

CAS号：73341-72-7

英文别名：(15R)-6,17-Didemethoxy-15-methoxy-6​-methyl-11-O-methyl-geldanamycin

分子量：558.67

分子式：C₃₀H₄₂N₂O₈

纯度：见爱必信官网

外观：见爱必信官网

保存方法：Desiccate at -20° C

描述：Macbecin I is an ansamycin antibiotic compound that inhibits Hsp90 activity (IC50 = 2 μM) by binding to the ATP-binding site. Macbecin I exhibits antitumor and cytocidal activities (IC50 ~ 0.4 μM) by causing degradation of key oncogenic client proteins such as ErbB2 and cRaf1. Macbecin I displays higher potency and affinity than geldanamycin.

应用：An ansamycin antibiotic inhibitor of Hsp90 activity

产品信息订购：

产品更多信息请进入爱必信网站咨询