Icariin,淫羊藿提取物,489-32-7

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试剂描述：

产品名称：Icariin

产品别名：4′-O-methyl-8-γ,γ-dimethylallylkaempferol-3-rhamnoside-7-glucoside

CAS号：489-32-7

英文别名：4′-O-methyl-8-γ,γ-dimethylallylkaempferol-3-rhamnoside-7-glucoside

分子量：676.66

分子式：C₃₃H₄₀O₁₅

纯度：≥97%

外观：Brown powder

保存方法：Store at RT

描述：

Icariin is an inhibitor of human recombinant PDE5 with an IC₅₀ value of 5.9 μM. It is a prenylated flavonol that has been shown to have anti-cancer and antioxidant activity. At a concentration of 1 x 107 mol/L, Icariin induces differentiation of cardiomyocytes and upregulates the expression of cardiac genes. At 20 μg/ml, Icariin increases the proliferation and differentiation of cultured human osteoblasts, which appears to be mediated in part by upregulating bone morphogenetic protein 2 mRNA.

应用：An inhibitor of recombinant PDE5

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