GM 1489,(3R)-3-[[(2S)-3-(1H-indol-3-yl)-1-oxo-1-[[(1S)-1-phenylethyl]amino]propan-2-yl]carbamoyl]-5-methylhexanoic acid,170905-75-6

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试剂描述：

产品名称：GM 1489

产品别名：N-[(2R)-2-(Carboxymethyl)-4-methylpentanoyl]-L-tryptophan-(S)-methyl-benzylamide

CAS号：170905-75-6

英文别名：N-[(2R)-2-(Carboxymethyl)-4-methylpentanoyl]-L-tryptophan-(S)-methyl-benzylamide

分子量：463.57

分子式：C₂₇H₃₃N₃O₄

纯度：>95%

外观：见爱必信官网

保存方法：Store at -20° C

描述：GM 1489 is a potent broad-range inhibitor of MMP (matrix metalloproteinases). Inhibits MMPs in vitro (K_i = 0.2 nM for MMP-1; K_i = 500 nM for MMP-2; K_i = 20 μM for MMP-3; Ki = 100 nM for MMP-8; and K_i = 100 nM for MMP-9). GM 1489 also reduces the inflammatory and the hyperproliferative responses that occur following topical phorbol ester application.

应用：A potent broad-range inhibitor of matrix metalloproteinases

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