CGS 35066,CGS 35066,α-[(S)-(Phosphonomethyl)amino]-3-dibenzofuranpropanoicacid,261619-50-5

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试剂描述：

产品名称：CGS 35066

产品别名：α-[(S)-(Phosphonomethyl)amino]-3-dibenzofuranpropanoic acid

CAS号：261619-50-5

英文别名：α-[(S)-(Phosphonomethyl)amino]-3-dibenzofuranpropanoic acid

分子量：349.28

分子式：C₁₆H₁₆NO₆P

纯度：>98%

外观：见爱必信官网

保存方法：Desiccate at room temperature

描述：CGS 35066 is a a potent endothelin-converting enzyme (ECE) inhibitor. When compared to neutral endopeptidase 24.11, it displays > 100-fold selectivity (IC50 values are 22 and 2300 nM respectively). Another interesting property of CGS 35066 is that it blocks the hypertensive effects induced by big ET-1 in vitro and is able to reduce the magnitude of cerebral vasospasm following subarachnoid hemorrhage (SAH).

应用：A potent endothelin-converting enzyme (ECE) inhibitor

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