Cdk2/9 Inhibitor,Cdk2/9 Inhibitor,507487-89-0

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产品名称：Cdk2/9 Inhibitor

产品别名：4-methyl-5-[2-(3-nitroanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine

CAS号：507487-89-0

英文别名：4-methyl-5-[2-(3-nitroanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine

分子量：328.34

分子式：C₁₄H₁₂N₆O₂S

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外观：见爱必信官网

保存方法：Store at 4° C

描述：Cdk2/9 Inhibitor is a cell-permeable aminopyrimidinyl compound that acts as a potent and ATP-competitive inhibitor of Cdk2/E and Cdk9/T1. Also inhibits GSK-3β, Cdk4/D, Cdk7/H, Cdk1/B, and Abl at higher concentrations, but exhibits little activity towards 9 other kinases. Cdk2/9 Inhibitor has been shown to inhibit phosphorylation of cellular Cdk substrates, pRb and RNA polymerase II, and Cdk2-mediated S-phase transition.

应用：A cell-permeable aminopyrimidinyl compound

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