C-12 NBD-dihydro-Ceramide,N-[(2S,3R)-1,3-Dihydroxy-2-octadecanyl]-12-[(7-nitro-2,1,3-benzox adiazol-4-yl)amino]dodecanamide,474943-05-0

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产品名称：C-12 NBD-dihydro-Ceramide

产品别名：N-C12-NBD-D-erythro-dihydro-Sphingosine

CAS号：474943-05-0

英文别名：N-C12-NBD-D-erythro-dihydro-Sphingosine

分子量：661.9

分子式：C₃₆H₆₃N₅O₆

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保存方法：Store at -20° C

描述：C-12 NBD-dihydro-Ceramide compound is a fluorescent ceramide analog which contains a saturated bond in the C4-C5 position of the sphingosine backbone. C-12 NBD ceramide, is a fluorescent ceramidase substrate which can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources. C-12 NBD-dihydro-ceramide may exhibit reduced activity in ceramidase assays compared to C-12 NBD ceramide. This is based on the observation that saturation of the C4-C5 sphingosine bond in C16-ceramide results in approximately a 10-fold reduction in efficiency as a substrate for rat brain ceramidase compared to the unsaturated substrate. Yet, experimental characterization of C-12 NBD-dihydro-ceramide as a ceramidase substrate needs to be performed.

应用：A fluorescent ceramidase substrate

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