3-Bromopyruvic acid hydrate,3-溴庚酸,206860-50-6

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产品名称：3-Bromopyruvic acid hydrate

产品别名：Bromopyruvate; 3-Bromo-2-oxopropionic acid

CAS号：206860-50-6

英文别名：Bromopyruvate; 3-Bromo-2-oxopropionic acid

分子量：166.96

分子式：C₃H₃BrO₃

纯度：≥97%

外观：Crystalline

保存方法：Store at 4° C

描述：3-Bromopyruvic acid is a brominated derivative of pyruvic acid , which inhibits HXK II (hexokinase II) in cancer cells. As a result of this inhibition the cells are unable to metabolize glucose into ATP directly. Studies conducted on MCF-7 breast cancer cells show that 3-Bromopyruvic acid hydrate reduces the expression of Bcl-2, c-Myc and mutant p53, which are involved in the cell death signal transduction pathway. Alternate studies indicate that 3-Bromopyruvic acid hydrate is a very selective antibiotic, inhibiting the growth of certain yeasts.

应用：An affinity label for cysteine residues and potential anti-cancer agent

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