Pyrazole N-Demethyl Sildenafil-d3,

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试剂描述：

产品名称：Pyrazole N-Demethyl Sildenafil-d3

产品别名：

CAS号：见爱必信官网

英文别名：

分子量：463.57

分子式：C₂₁H₂₅D₃N₆O₄S

纯度：见爱必信官网

外观：white to off-white

保存方法：Store at -20° C

描述：Pyrazole N-Demethyl Sildenafil-d3 is a deuterium-labelled derivative of Sildenafil . Sildenafil is a selective inhibitor of the type 5 cGMP phosphodiesterase (PDE5 inhibitor) which catalyzes the hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP). As a PDE5 inhibitor, Sildenafil has been reported to enhance neuro-, synapto- and angiogenesis in rat models of stroke and also is reported to be a mild vasodilator. Sildenafil has also been shown to prevent indomethacin-induced small intestinal ulceration formation through an NO/cGMP- dependent mechanism.

应用：A deuterium-labelled derivative of Sildenafil

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