公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)! 试剂描述: 产品名称:PETCM 产品别名:Alpha-(三氯甲基)-4-吡啶乙醇 CAS号:10129-56-3 英文别名:1,1,1-trichloro-3-pyridin-4-ylpropan-2-ol 分子量:240.5 分子式:C8H8Cl3NO 纯度:≥95% 外观:Powder 保存方法:Store at 4° C 描述:PETCM is an activator of caspase-3 and a stimulator of apoptosome formation in HeLa cell cytosols. In addition, studies suggest that PETCM can reverse the inhibitory effects of putative HLA-DR-associated proteins (PHAP) on caspase-3 activation. Since caspase-3 activation is dependent on apoptosome formation, prothymosin α can inhibit the activation of caspase-3 by disrupting the formation of the apoptosome somewhere upstream in this regulatory pathway. Studies suggest that PETCM can eliminate the inhibitory effects of prothymosin α by acting as an antagonist and allwing PHAP to stimulate apoptosome formation at a physiological concentration of deoxyadenosine triphosphate. 应用:A caspace-3 activator in cell extracts 产品信息订购: 产品货号 | 产品名称 | 规格 | 价格 | 大包装及货期 | abs42024906 | PETCM | 10mg | 510 | 立即咨询 | 产品更多信息请进入爱必信网站咨询 |