PEPA,2,6-Difluoro-4-[2-(phenylsul-fonyl-amino)-ethyl-thio]-phenoxy-acet-amide,141286-78-4

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试剂描述：

产品名称：PEPA

产品别名：2,6-Difluoro-4-[2-(phenylsul­fonyl­amino)­ethyl­thio]­phenoxy­acet­amide

CAS号：141286-78-4

英文别名：2,6-Difluoro-4-[2-(phenylsul­fonyl­amino)­ethyl­thio]­phenoxy­acet­amide

分子量：402.44

分子式：C₁₆H₁₆F₂N₂O₄S₂

纯度：98%

外观：Powder

保存方法：Store at room temperature

描述：PEPA is an allosteric potentiator of AMPA desensitization. PEPA decreases the rate of onset of desensitization and potentiates steady-state equilibrium currents induced by Glu with splic variant and subunit selectivity. PEPA enhances post-ischemic memory impairment in rats post i.v. administration. AMPA is a transmembrane glutamate receptor composed of the subunits GluR-1,2,3,4. PEPA is an activator of GluR.

应用：An allosteric potentiator of AMPA desensitization

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