PD 81,723,(2-氨基-4,5-二甲基-3-噻吩)-[3-(三氟甲基)苯基]甲酮,132861-87-1

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试剂描述：

产品名称：PD 81,723

产品别名：(2-氨基-4,5-二甲基-3-噻吩)-[3-(三氟甲基)苯基]甲酮

CAS号：132861-87-1

英文别名：(2-amino-4,5-dimethylthiophen-3-yl)-[3-(trifluoromethyl)phenyl]methanone

分子量：299.31

分子式：C₁₄H₁₂F₃NOS

纯度：≥99%

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保存方法：Store at room temperature

描述：PD 81723 is an allosteric potentiator at Adenosine A1-R that acts via agonist-dependent and independent mechanisms. PD 81723 enhances the functional effects of adenosine and adenosine analogs. This compound also inhibits basal and forskolin-stimulated A cyclase (adenylyl cyclase, AC) activity in Adensosine A1-R expressed in CHO cells, possibly via direct potentiation of constitutive receptor activity or by direct inhibition of A cyclase (adenylyl cyclase, AC).

应用：An allosteric potentiator that increases the functional effects of adenosine and adenosine analogs

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