PD 184161,5-bromo-2-(2-chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide,212631-67-9

公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）!

试剂描述：

产品名称：PD 184161

产品别名：5-bromo-2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluoro-benzamide

CAS号：212631-67-9

英文别名：5-bromo-2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluoro-benzamide

分子量：557.56

分子式：C₁₇H₁₃BrClF₂IN₂O₂

纯度：≥98%

外观：Crystalline solid

保存方法：Store at -20° C

描述：PD 184161 is a strong and selective inhibitor of MEK-1 and MEK-2 with an IC50 value that ranges from 10-100 nM. 1 More effective at inhibiting phosphorylation of ERK1/2 than the selective MEK inhibitors, PD098059 and U0126. PD 184161 is structurally related to clinically-studied MEK inhibitors PD184352 (CI-1040) and PD 325901 and has been shown to inhibit cell proliferation, induce apoptosis, and possess anti-tumor activity in MEK-dependent cancers.

应用：A strong and selective inhibitor of MEK1/2

产品信息订购：

产品更多信息请进入爱必信网站咨询