NVP DPP 728 dihydrochloride,6-[2-[[2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl]amino]ethylamino]pyridine-3-carbonitrile,dihydrochloride,247016-69-9

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产品名称：NVP DPP 728 dihydrochloride

产品别名：6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidin­yl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbono­nitrile dihydrochloride

CAS号：247016-69-9

英文别名：6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidin­yl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbono­nitrile dihydrochloride

分子量：371.27

分子式：C₁₅H₁₈N₆O•2HCl

纯度：≥98%

外观：Powder

保存方法：Desiccate at room temperature

描述：NVP DPP 728 dihydrochloride is a DPP-IV (CD26) inhibitor. NVP DPP 728 dihydrochloride displays >15,000 fold selectivity over DPP-II and a range of Pro-cleaving proteases. The compound is shown to improve Glc tolerance, increase GLP-1 and Insuling levels, augments insulin secretion and GLUT-2 levels, and preserves islet size.

应用：A DPP-IV (CD26) inhibitor

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