N-Desmethyl Diltiazem Hydrochloride,N-Desmethyl Diltiazem Hydrochloride,130606-60-9

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产品名称：N-Desmethyl Diltiazem Hydrochloride

产品别名：N-Demethyldiltiazem; N-Monodesmethyldiltiazem

CAS号：130606-60-9

英文别名：N-Demethyldiltiazem; N-Monodesmethyldiltiazem

分子量：436.95

分子式：C₂₁H₂₄N₂O₄S•HCl

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保存方法：Store at -20° C

描述：N-Desmethyl Diltiazem Hydrochloride is a metabolite of Diltiazem , a non-dihydropyridine calcium channel blocker. Studies show that N-Desmethyl Diltiazem Hydrochloride selectively inhibits CYP3A4. This enzyme is useful in a variety of cellular reactions such as the oxidation of xenobiotics. In addition, N-Desmethyl Diltiazem Hydrochloride inhibits testosterone 6β-hydroxylation which is mediated by CYP3A4. Although Diltiazem acts as an inhibitor of CYP3A4, it can also be metabolized by the enzyme. It is known that Diltiazem acts as a vasodilator increasing blood flow around peripheral and coronary vessels.

应用：A calcium channel blocker

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