N,N-Didesmethyl-O-desmethyl rac-Venlafaxine 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester,

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产品名称：N,N-Didesmethyl-O-desmethyl rac-Venlafaxine 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester

产品别名：

CAS号：见爱必信官网

英文别名：

分子量：551.58

分子式：C₂₇H₃₇NO₁₁

纯度：见爱必信官网

外观：white

保存方法：Store at -20° C

描述：N,N-Didesmethyl-O-desmethyl rac-Venlafaxine 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester is an intermediate for the synthesis of N,N-Didesmethyl-O-desmethyl-(rac-Venlafaxine) Glucuronide . N,N-Didesmethyl-O-desmethyl rac-Venlafaxine 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester is also a derivative of Venlafaxine . Venlafaxine is a derivative of phenylethylamine which is reported to facilitate neurotransmission within the central nervous system via blocking the presynaptic reuptake of neuroamines such as serotonin (5-hydroxytryptamine; 5-HT) and noradrenaline (norepinephrine). Velanfaxine is also reported to be a weak inhibitor of dopamine reuptake. In vitro studies indicate that Venlafaxine does not demonstrate significant activity for muscarinic, histaminergic or α-1 adrenergic receptors. The metabolism of venlafaxine is reported to occur by cytochrome P450 (CYP) enzyme CYP2D6 yielding O-desmethylvenlafaxine. A lesser metabolite, N-desmethylvenlafaxine is produced by CYP3A4.

应用：A useful synthetic intermediate

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