N-(4-Acetamidophenyl)indomethacin Amide,N-(4-acetamidophenyl)-2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetamide,261766-23-8

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产品名称：N-(4-Acetamidophenyl)indomethacin Amide

产品别名：N-(4-acetamidophenyl)-2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetamide

CAS号：261766-23-8

英文别名：N-(4-acetamidophenyl)-2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetamide

分子量：489.95

分子式：C₂₇H₂₄ClN₃O₄

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外观：见爱必信官网

保存方法：Store at -20° C

描述：N-(4-Acetamidophenyl)indomethacin Amide is a potent and selective reversible Cox-2 inhibitor. N-(4-Acetamidophenyl)indomethacin Amide inhibits human Cox-2 with IC₅₀ of 0.1 μM and ovine Cox-2 with IC₅₀ of 0.625 μM. N-(4-Acetamidophenyl)indomethacin Amide is about 400 times less potent as an inhibitor of human Cox-1 and 80 times less potent as an inhibitor of ovine Cox-1. N-(4-Acetamidophenyl)indomethacin Amide shows anti-inflammatory, antiangiogenic, and cancer chemopreventive activity in various experimental models.

应用：A selective reversible Cox-2 inhibitor

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