Monastrol,ethyl 4-(3-hydroxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate,254753-54-3

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试剂描述：

产品名称：Monastrol

产品别名：4-(3-Hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4H-pyrimidin-5-carboxylic acid ethyl ester

CAS号：254753-54-3

英文别名：4-(3-Hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4H-pyrimidin-5-carboxylic acid ethyl ester

分子量：292.35

分子式：C₁₄H₁₆N₂O₃S

纯度：≥95%

外观：见爱必信官网

保存方法：Store at -20° C

描述：Monastrol is a potent, cell-permeable, small molecule mitosis inhibitor that does not interact with tubulin. Monastrol arrests cells in mitosis and specifically inhibits the motility of the mitotic kinesin Eg5, a motor protein required for mitotic spindle formation and maintenance (IC₅₀ = 14 μM).

应用：A kinesin Eg5 inhibitor which arrests cells in mitosis

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