公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)! 试剂描述: 产品名称:Recombinant Human Tyrosine Kinase ErbB-2 产品别名:重组人酪氨酸激酶erbB-2;ErbB2 CAS号:见爱必信官网 英文别名:ErbB2 分子量:见爱必信官网 分子式:见爱必信官网 纯度:0.95 外观:Filtered colorless solution(The ErbB-2 filtered (0.4µm) solution in 0.05M Acetate buffer pH-4 and 5% trehalose). 保存方法:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. 描述: HER-2/neu (erbB-2) encodes an 185-kDa orphan receptor tyrosine kinase that is constitutively active as a dimer and displays potent oncogenic activity when overexpressed. Herstatin, as the product of alternative HER-2 transcript, retains intron 8. The herstatin mRNA is expressed in normal human fetal kidney and liver, but is at reduced levels relative to p185HER-2 mRNA in carcinoma cells that contain an amplified HER-2 gene. Herstatin appears to be an inhibitor of p185HER-2, because it disrupts dimers, reduces tyrosine phosphorylation of p185, and inhibits the anchorage-independent growth of transformed cells that overexpress HER-2. ErbB-2 Human Recombinant is a 43.4 kDa protein containing 397 amino acid residues of the human Herstatin, and an extra Methionine at N-Terminal (underlined), produced in E.coli. 应用:见爱必信官网 产品信息订购: 产品货号 | 产品名称 | 规格 | 价格 | 大包装及货期 | abs44074612 | Recombinant Human Tyrosine Kinase ErbB-2 | 5ug | 940 | 立即咨询 | 产品更多信息请进入爱必信网站咨询 |