公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)! YZ剂描述: 产品名称:Mito-TEMPO 产品别名:见爱必信官网 英文别名:Mito-TEMPO 靶点:Mitochondrial Metabolism CAS:1334850-99-5 纯度:98% 外观:见爱必信官网 保存方法:store at -20℃ for one year(Powder) 描述:Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic with superoxide and alkyl radical scavenging properties. 溶解性: In Vitro: DMSO : 125 mg/mL (245.08 mM; Need ultrasonic) H2O : 60 mg/mL (117.64 mM; Need ultrasonic) Preparing Stock Solutions ConcentrationSolventMass | 1 mg | 5 mg | 10 mg |
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1 mM | 1.9607 mL | 9.8033 mL | 19.6067 mL | 5 mM | 0.3921 mL | 1.9607 mL | 3.9213 mL | 10 mM | 0.1961 mL | 0.9803 mL | 1.9607 mL |
*请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液,并请注意储备液的保存方式和期限。 In Vivo: 请根据您的实验动物和给YF式选择适当的溶解方案,配制前请先配制澄清的储备液,再依次添加助溶剂(为保证实验结果的可靠性,体内实验的工作 液,建议您现用现配,当天使用;澄清的储备液可以根据储存条件,适当保存;以下溶剂前的百分比是指该溶剂在您配制终溶液中的体积占比): 1. 请依序添加每种溶剂: 10% DMSO 40% PEG300 5% Tween-80 45% saline Solubility: ≥ 2.25 mg/mL (4.41 mM); Clear solution 2. 请依序添加每种溶剂: 10% DMSO 90% (20% SBE-β-CD in saline) Solubility: ≥ 2.25 mg/mL (4.41 mM); Clear solution 3. 请依序添加每种溶剂: 10% DMSO 90% corn oil Solubility: ≥ 2.25 mg/mL (4.41 mM); Clear solution
* 体外研究: 体内研究: Mito-TEMPO (MT) greatly attenuates the increase in ALT activities and reduces the areas of necrosis at both time points, indicating that the protection by Mito-TEMPO is sustained until at least 24 h post-APAP. Mito-Tempo could induce secondary apoptosis in the late phase of APAP hepatotoxicity. Mito-Tempo induces secondary apoptosis after APAP overdose by inhibition of RIP3. 产品信息订购: 产品货号 | 产品名称 | 规格 | 价格 | 大包装及货期 | abs820571 | Mito-TEMPO | 5mg | 2880 | 立即咨询 | 产品更多信息请进入爱必信网站咨询 |