Arachidonoyl Glycine-d8

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产品名称：Arachidonoyl Glycine-d8

产品别名：NAGly-d₈;N-Arachidonyl Glycine-d₈;

CAS号：1159908-44-7

英文别名：Arachidonoyl Glycine-d8

分子量：369.6

分子式：C₂₂H₂₇D₈NO₃

纯度：≥99% deuterated forms (d₁-d₈)

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保存方法：Store at -20℃

描述：Arachidonoyl glycine-d₈ (NAGly-d₈) contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of NAGly by GC- or LC-mass spectrometry. NAGly has been isolated from cell cultures treated with arachidonoyl ethanolamide (AEA),¹ from extracts of mammalian brain,^2,3 and has also been synthesized as an analog of AEA for structure/activity testing.⁴ NAGly may be produced endogenously via oxidation of AEA, or by transacylation of arachidonoyl coenzyme A. NAGly is reported to have analgesic activities in whole animal experiments.^1,2,3 Since it seems to be a very poor ligand for the CB₁ receptor,⁴ these effects are probably mediated via other signalling pathways.

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