公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)! 试剂描述: 产品名称:N-[4-[(2S)-3-[[2-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropoxy]phenyl]-methanesulfonamide 产品别名:N-[4-[3-[2-(3,4-dichlorophenyl)ethylamino]-2-hydroxypropoxy]phenyl]methanesulfonamide CAS号:457897-92-6 英文别名:N-[4-[3-[2-(3,4-dichlorophenyl)ethylamino]-2-hydroxypropoxy]phenyl]methanesulfonamide 分子量:433.35 分子式:C18H22Cl2N2O4S 纯度:见爱必信官网 外观:见爱必信官网 保存方法:Store at -20° C 描述:N-Methyl-D-aspartate (NMDA) receptors are Ca2+ permeable ligand-gated channels of the central nervous system that are activated after binding of the co-agonists glutamate and glycine. This chemical is a propanolamine that potently, selectively, and non-competitively antagonizes the NR2B subunit of NMDA receptors (IC50 = 50 nM). It does not inhibit NR1, NR2A, NR2C, and NR2D subunits and has no significant effects on α-amino-3-hydroxy-5-methyl-4-isoxazolepropioinic acid (AMPA) or kainate receptors. This compound is neuroprotective, since it prevents NMDA-triggered release of lactate dehydrogenase from cultured cortical neurons. Also, when administered intraperitoneally, reduces brain infarct volume resulting from transient ischemia via carotid artery occlusion. 应用:见爱必信官网 产品信息订购: 产品货号 | 产品名称 | 规格 | 价格 | 大包装及货期 | abs42154026 | N-[4-[(2S)-3-[[2-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropoxy]phenyl]-methanesulfonamide | 5mg | 2262 | 立即咨询 | 产品更多信息请进入爱必信网站咨询 |