N-Desmethyl Sildenafil,N-去甲基西地那非,139755-82-1

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产品名称：N-Desmethyl Sildenafil

产品别名：5-[2-Ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one; Desmethylsildenafil

CAS号：139755-82-1

英文别名：5-[2-Ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one; Desmethylsildenafil

分子量：460.55

分子式：C₂₁H₂₈N₆O₄S

纯度：≥99%

外观：见爱必信官网

保存方法：Store at 4° C

描述：N-Desmethyl Sildenafil is a metabolite of Sildenafil . Sildenafil is a selective inhibitor of the type 5 cGMP phosphodiesterase (PDE5 inhibitor) which catalyzes the hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP). As a PDE5 inhibitor, Sildenafil has been reported to enhance neuro-, synapto- and angiogenesis in rat models of stroke and also is reported to be a mild vasodilator. Sildenafil has also been shown to prevent indomethacin-induced small intestinal ulceration formation through an NO/cGMP- dependent mechanism.

应用：A potential selective type 5 phosphodiesterase inhibitor

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