Acetyl Podocarpic Acid Anhydride,Acetyl Podocarpic Acid Anhydride,344327-48-6

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产品名称：Acetyl Podocarpic Acid Anhydride

产品别名：acetyl-podocarpic dimer

CAS号：344327-48-6

英文别名：acetyl-podocarpic dimer

分子量：614.75

分子式：C₃₈H₄₆O₇

纯度：见爱必信官网

外观：见爱必信官网

保存方法：Store at -20° C

描述：Acetyl podocarpic acid anhydride (APD) is a potent, semi-synthetic liver X receptor (LXR) agonist derived from extracts of the mayapple. APD forms a heterodimer with the retinoid X receptor (RXR), and together these compounds, acting through LXR, induce the expression of the ABCA1 reverse cholesterol transporter and inhibit the overall absorption of cholesterol (ED₅₀ = 1 nM). In transient transactivation assays, acetyl podocarpic acid anhydride was found to be approximately 1,000 times more potent than 22(R)-hydroxy cholesterol. APD can be used as a positive control for the testing of LXR agonists.

应用：A potent, semi-synthetic liver X receptor agonist

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