Y 134,[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methanone,849662-80-2

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试剂描述：

产品名称：Y 134

产品别名：[6-Hydroxy-2-(4-hydroxyphenyl)benzo­[b]thien-3-yl]-[4-[4-(1-methylethyl)-1-piperazinyl­]phenyl]methanone

CAS号：849662-80-2

英文别名：[6-Hydroxy-2-(4-hydroxyphenyl)benzo­[b]thien-3-yl]-[4-[4-(1-methylethyl)-1-piperazinyl­]phenyl]methanone

分子量：472.6

分子式：C₂₈H₂₈N₂O₃S

纯度：≥98%

外观：见爱必信官网

保存方法：Desiccate at room temperature

描述：Y 134 is a selective estrogen receptor modulator (SERM), selective for ERα. Non cross-reactive with mineralocorticoid, glucocorticoid, androgen, and progesterone receptors. Y 134 exhibits agonist behaviors in bone and antagonist behavior in reproductive tissue. Y 134 decreases activity of estrogen-stimulated proliferation of ER+ human breast cancer MCF-7 and T47D cells.

应用：A SERM displaying selectivity for ERα over ERβ

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