N-Desmethyl Clozapine-d8,N-Desmethyl Clozapine-d8,6104-71-8(unlabeled)

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产品名称：N-Desmethyl Clozapine-d8

产品别名：8-Chloro-11-(1-piperazinyl-d8)-5H-dibenzo[B,E][1,4]diazepine hydrochloride

CAS号：6104-71-8(unlabeled)

英文别名：8-Chloro-11-(1-piperazinyl-d8)-5H-dibenzo[B,E][1,4]diazepine hydrochloride

分子量：357.26

分子式：C₁₇H₉D₈ClN₄•HCl

纯度：见爱必信官网

外观：Crystalline

保存方法：Store at -20° C

描述：N-Desmethyl Clozapine-d8 (norclozapine) is a deuterium-labeled, major metabolite of Clozapine which is reported to act as a highly potent and selective 5-HT_2c serotonin receptor antagonist. In studies with in vitro microsomal preparations of human liver, Clozapine was noted to metabolize to N-Desmethyl Clozapine and Clozapine N-oxide . As a method of detection, reversed-phase HPLC has been reported as an identification method for Clozapine and its two major metabolites. Additional HPLC studies have reported the use of deuterium-labeled compounds in detecting Clozapine and metabolites such as N-Desmethyl Clozapine.

应用：A deuterium labeled potent and selective 5-HT2c serotonin receptor antagonist

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