Ethylenedioxy Spiperone,Ethylenedioxy Spiperone,54080-21-6(non-salt)

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产品名称：Ethylenedioxy Spiperone

产品别名：Ethylenedioxy Spiperone

CAS号：54080-21-6(non-salt)

英文别名：Ethylenedioxy Spiperone

分子量：475.98

分子式：C₂₅H₃₁ClFN₃O₃

纯度：见爱必信官网

外观：off-white

保存方法：Store at 4° C

描述：Ethylenedioxy Spiperone is an analogue of Spiperone . Spiperone is an 5-HT_2A serotonin and selective D₂-like dopamine receptor antagonist (K_i values are 0.06, 0.6, 0.08, ~ 350, ~ 3500 nM for D₂, D₃, D₄, D₁ and D₅ receptors respectively). Although the well known role of Spiperone in research studies indicates it acts as an antagonist of either 5-HT₂ or D₂ receptors, Spiperone has also been reported to act through a protein tyrosine kinase-coupled phospholipase C-dependent pathway. Spiperone was observed to act independent of either 5-HT₂ or D₂ receptors as reported In a study investigating the role of Spiperone and Ca²⁺ activated Cl^- (CaCC) in human cystic fibrosis (CF) airway epithelial cell monolayers in vitro.

应用：An analogue of Spiperone

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