BMS 193885,dimethyl 4-[3-[3-[4-(3-methoxyphenyl)piperidin-1-yl]propylcarbamoylamino]phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate,186185-03-5

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产品名称：BMS 193885

产品别名：dimethyl 4-[3-[3-[4-(3-methoxyphenyl)piperidin-1-yl]propylcarbamoylamino]phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

CAS号：186185-03-5

英文别名：dimethyl 4-[3-[3-[4-(3-methoxyphenyl)piperidin-1-yl]propylcarbamoylamino]phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

分子量：680.79

分子式：C₃₃H₄₂N₄O₆ C₃H₆O₃

纯度：>98%

外观：见爱必信官网

保存方法：Desiccate at 4° C

描述：BMS 193885 is a potent, competitive NPY1-R antagonist (K_i = 3.3 nM, IC₅₀ = 5.9 nM) that displays > 47, > 100, > 160, > 160 and > 160-fold selectivity over σ1, α1, NPY2-R, NPY4-R and NPY5-R receptors respectively. Reduces food intake and body weight via central NPY1-R inhibition and is a brain penetrant.

应用：A competitive NPY1-R antagonist

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