Avenanthramide-C methyl ester,methyl 2-[3-(3,4-dihydroxyphenyl)prop-2-enoylamino]-5-hydroxybenzoate,955382-52-2

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试剂描述：

产品名称：Avenanthramide-C methyl ester

产品别名：methyl 2-[3-(3,4-dihydroxyphenyl)prop-2-enoylamino]-5-hydroxybenzoate

CAS号：955382-52-2

英文别名：methyl 2-[3-(3,4-dihydroxyphenyl)prop-2-enoylamino]-5-hydroxybenzoate

分子量：329.31

分子式：C₁₇H₁₅NO₆

纯度：≥95%

外观：见爱必信官网

保存方法：Store at -20° C

描述：Avenanthramide-C methyl ester inhibits NF-κB activation by blocking the phosphorylation of IKK and IκB (IC₅₀ ~ 40 μM). Through this mechanism, avenanthramide-C methyl ester dose dependently inhibits the secretion and expression of IL-6, IL-8, and MCP-1 in human aortic endothelial cells.

应用：An inhibitor NF-κB activation

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