Amiloride, 5-(N,N-Dimethyl)-, hydrochloride,5-(N,N-二甲基)阿米洛利 盐酸盐,1214-79-5

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试剂描述：

产品名称：Amiloride, 5-(N,N-Dimethyl)-, hydrochloride

产品别名：3-Amino-N-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride; DMA.HCl; 5-(N,N-Dimethyl)amiloride.HCl

CAS号：1214-79-5

英文别名：3-Amino-N-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride; DMA.HCl; 5-(N,N-Dimethyl)amiloride.HCl

分子量：294.14

分子式：C₈H₁₂ClN₇O•HCl

纯度：≥97%

外观：见爱必信官网

保存方法：Store at 4° C

描述：Amiloride, 5-(N,N-Dimethyl)-, hydrochloride (DMA) is an inhibitor of the Na⁺-H⁺ exchanger (NHE) with stronger potency than the parent compound, amiloride . DMA and other amiloride derivatives have been employed in elucidating the dynamics and activity of the NHE. Inhibition of the NHE by DMA was demonstrated to protect against severe ischemia/reperfusion-induced cardiac contractile dysfunction by normalizing tissue Na⁺ levels and preserving contractile function recovery during reperfusion.

应用：An Na⁺-H⁺ exchanger inhibitor

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