产品名称:CD19抗体,Anti-CD19抗体应有尽有
中文名称:CD19抗体
英文名称:Anti-CD19
产品编号:byk-0079R
产品规格:0.1ml/0.2ml
产品用途:科研实验
亚 型: IgG
贮 存: 贮存于-20℃
抗体的异质性。抗体的组成极为复杂,是由成千上万、多种多样的免疫球蛋白(Ig)分子所组成。这些Ig分子在形状、大小、结构以及氨基酸的组成和排列上,既相似,又有差别。由于有差别,它们的电泳活性就有很大的变化。
CD19抗体,Anti-CD19抗体应有尽有 品说明:
CD19 is a transmembrane glycoprotein that is delectively expressed on the cell surface of B-lymphocytes,where it activates intracellular signaling cascades involving both Ras and phosphatidylinositol 3-kinase pathways.Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CD19抗体,Anti-CD19抗体应有尽有 关产品:
Anti-Mcl-1(myeloid cell leukemia 1) 髓样细胞白血病-1抗体
Anti-MDM2 (urine double minute 2) 双微体2癌基因抗体
Anti-MDR1(multidrug resistance 1) 多药耐药蛋白抗体
Anti-MEF2(myocyte enhancer-binding factor 2) 肌细胞增强因子2抗体
Anti-Megsin/SER—PINB7 丝氨酸(或半胱氨酸)蛋白酶YZ剂B7抗体
Anti-Melamine 三聚氰胺抗体
Anti-Melamine 三聚氰胺抗体
Anti-Melan-A/MART-1 黑色素瘤相关抗原/黑色素-A抗体
Anti-M-enk 抗甲硫氨酸脑啡肽抗体
Anti-MEK1/MAPKK1/MEKK1(mitogen activated protein kinase kinase 1) MEK1/MAPKK1抗体(N-端)
抗体结构:
抗体是具有4条多肽链的对称结构,其中2条较长、相对分子量较大的相同的重链(H链);2条较短、相对分子量较小的相同的轻链(L链)。链间由二硫键和非共价键联结形成一个由4条多肽链构成的单体分子。轻链有κ和λ两种,重链有μ、δ、γ、ε和α五种。 整个抗体分子可分为恒定区和可变区两部分。在给定的物种中,不同抗体分子的恒定区都具有相同的或几乎相同的氨基酸序列。可变区位于"Y"的两臂末端。在可变区内有一小部分氨基酸残基变化特别强烈,这些氨基酸的残基组成和排列顺序更易发生变异区域称高变区。高变区位于分子表面,多由17个氨基酸残基构成,少则只有2 ~ 3个。高变区氨基酸序列决定了该抗体结合抗原抗原的特异性。一个抗体分子上的两个抗原结合部位是相同的,位于两臂末端称抗原结合片段(antigen-binding fragment, Fab)。"Y"的柄部称结晶片段(crystalline fragment,FC),糖结合在FC 上。