Glucose-conjugated MGMT inhibitor,382607-78-5

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YZ剂描述：

产品名称：Glucose-conjugated MGMT inhibitor

产品别名：(2R,3R,4S,5S,6R)-2-[8-[2-amino-6-[(4-bromothiophen-2-yl)methoxy]purin-9-yl]octoxy]-6-(hydroxymethyl)oxane-3,4,5-triol

英文别名：Glucose-conjugated MGMT inhibitor

靶点：DNA Methyltransferase

CAS：382607-78-5

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描述：Glucose-conjugated MGMT inhibitor is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells.

溶解性：10 mM in DMSO

体外研究：

Glucose-conjugated MGMT inhibitor (O6BTG-octylglucoside) is a potent and non-toxic MGMT inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells.

体内研究：

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