Esomeprazole Magnesium,161973-10-0

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产品名称：Esomeprazole Magnesium

产品别名：埃索美拉唑镁

英文别名：Esomeprazole Magnesium

靶点：Proton Pump

CAS：161973-10-0

纯度：>98%

外观：白色或类白色结晶性粉末

保存方法：-20°C

描述：

Esomeprazole magnesium (Nexium) is a proton pump inhibitor which reduces gastric acid secretion through inhibition of H+/K+-ATPase in gastric parietal cells. By inhibiting the functioning of this enzyme, the drug prevents formation of gastric acid.

溶解性：Ethanol ：143 mg/mL (200.52 mM)
DMSO ：143 mg/mL (200.52 mM)

体外研究：

Esomeprazole magnesium is an inhibitor of H+, K+-ATPase.

体内研究：Esomeprazole magnesium (0.5, 5, 50 mg/kg/day, p.o.) produces increased gastric total antioxidant capacity, decreases gastric lipid peroxide levels, significantly increases superoxide dismutase levels, but shows no obvious effect on colonic lipid peroxide levels in mice.

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